Contract Research

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All CELLnTEC models are established using innovative media combined with novel 2D and 3D methods to maximize modeling accuracy.

These innovative models combined with a broad range of modern analytical methods and our long experience with the design of creative experimental approaches generate a powerful combination of skills which are now available for your next project.

We are experienced with the use of both human and rodent cells for the establishment of either undifferentiated stem/progenitor cell models or fully differentiated 3D models.  Ask us today what approaches we could propose for your next in vitro project.

 

The scientific team at CELLnTEC is dedicated to providing the absolute best in service and support, and continues to adhere to the following values:

  • Remain up-to-date with the latest science, and apply it to the development of novel experimental methods for both 2D and 3D in vitro models.
  • Listen carefully to the needs of our partners
  • Bring all our own experience to the task of designing a testing protocol which will deliver novel insights into the mechanism or active ingredient under investigation.
For further information, please contact servicesatcellntec [dot] com

 

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Cosmeceutical & Nutraceutical

Primary human epidermal keratinocytes, stained for adhesion markers in 2D culture,

Cosmetic Actives: The cosmetic industry is driven by the need for new actives and novel claims. In addition to a range of standard testing methods, we specialize in the development of novel approaches that deliver unique claims to differentiate your product in the market.   Our focus on new approaches has lead us to create exciting new stem cell-based methods, as well as anti-aging models in 2D and 3D, plus a host of other protocols to quantify novel mechanisms and end-points (see our Precision Models page). We work hard to be the best scientific partner for your in vitro testing needs - don't hesitate to contact us and ask what methods would be best suited to your next project.

Nutraceuticals: The use of functional foods and nutritional supplements to improve health and appearance is now really starting to gain momentum. However the industry remains limited by available methods for generating claims support, especially using in vitro methods. We are now beginning to expand our offerings in this area, and are keen to hear your needs, and to investigate how our extensive in vitro experience can support your next project.

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Biotech & Pharma

3D urothelial model established using primary rat urothelial cells.
Prostasphere isolated from primary human tumor biopsy.  Guzman-Ramirez 2009.

Toxicology: Precision models established using either primary human cells or long-term animal cells provide accurate modeling of the in vivo situation. These models can be established in either 2D or 3D culture, and are an ideal choice for either predictive toxicology screens, or investigation of mechanistic toxicology.

Stem Cells: CELLnTEC's highly precise approach to the development of culture media has been used to create a range of Progenitor Cell Targeted media that excel at the establishment of enriched cultures of stem and progenitor cells. These cells underlie all regeneration in the body, and are key targets in many pathologies.  Accordingly cells established using PCT media are ideally suited to the investigation stem cell biology and related mechanisms of disease.

Cancer Stem Cells: Recent work has shown that PCT media can also be used to establish progenitor cell cultures direct from primary prostate tumor tissue. Progenitor cells may be maintained in either mono-layer culture or as prostaspheres. Cells cultured as spheres were found to express both progenitor cell and tumor cell fusion proteins, and provides good evidence that this method is able to reliably establish cultures of cancer stem cells.

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