Melanocytes growing in CnT-PR-MH Homeostasis medium are significantly more responsive to treatment with a tyrosinsase inhibitor, and demonstrate larger reductions in melanin content in both neonatal and adult cells.
Homeostasis Medium
Cells growing in a medium designed for rapid proliferation or complete differentiation are receiving a strong set of signals from the culture medium.
These strong signals tend to reduce the responsiveness of cells to the external stimuli applied during experimentation.
To improve assay responsiveness, we have developed a melanocyte homeostasis medium known as Prime MH, in which cells demonstrate higher responsiveness to assay treatments, such as tyrosinase inhibitors for example.